Effect of Mast Cell Depletion on Wound Healing†

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Mast Cells and Wound Healing.

BACKGROUND Mast cells (MC) are ubiquitous resident cells, traditionally viewed as effector cells of allergic reactions that can store and synthesize de novo many mediators upon activation by a variety of stimuli. Exciting new insights are unveiling MC involvement in the pathogenesis of connective tissue disorders including wound healing and fibrosis. THE PROBLEM Abnormal wound repair is assoc...

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 1961

ISSN: 0022-202X

DOI: 10.1038/jid.1961.32